The town of Valle de Guadalupe and it's surrounding countryside are first seen via flashback and are depicted as tranquil. Everything seems to be, as is the case in the rest of the world, "business as usual" in this quiet area of Mexico.
Valle de Guadalupe, or at least, a fortified vineyard near the town, is revealed to be Strand's true location in the episode Ouroboros. It is promised to be a safe haven, stocked with food, water and supplies.
However, things are not as safe or as tranquil as they used to be in the episode Sicut Cervus. The local Parish Priest and his congregation are poisoned via communion wafer by Celia Flores in order to prevent them from killing a herd of infected that she has locked in her wine cellar. There are also numerous infected wandering around in the town and the surrounding countryside. Also, in order for The Abigail to make landfall near El Rosarito, she must first cross a military blockade that is being enforced by the Mexican Navy.
- While Strand mentions that he was heading to Rosarito for the safe house, the Abigail compound is actually located in Valle de Guadalupe, as mentioned by Nick in "Grotesque" and mentioned by showrunner Dave Erickson in an Entertainment Weekly interview. It is possible Strand mentioned Rosarito as where they would set course in order to travel to Valle de Guadalupe.